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Swiss-led study: Donor sex may influence transplant success
Wednesday, July 09, 2008
from
swissinfo.chThe results of a Swiss-led study on the long-term success of kidney transplants suggest that organs should be distributed to recipients of the same sex as the donor.
The findings, published in the British medical journal The Lancet, indicate that male recipients of female grafts have an increased risk of graft-versus-host disease.
"Consideration of sex should be integrated into future prospective analyses and decisions on organ allocation," the study's authors wrote.
Male recipients could probably profit from male kidneys, which contain higher nephron doses, researchers said. Nephron doses are the basic structural units of the organ; the higher the dose, the stronger the kidney.
Female recipients might not need the same number of nephrons as men, and could profit from the lower likelihood of rejection associated with a sex-matched donor kidney.
posted by Ivon, 12:39 PM
